When the county coroner arrived at Sam Sheppard's house in July of 1954, the pathologist was certain the case was open-and-shut: Sheppard, a headlines-courting doctor and serial philanderer, clearly had murdered his 31-year-old wife, Marilyn. Sheppard faced not one but two trials of the century in a case that reached the U.S. Supreme Court and continues to stir controversy to this day.